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Opioid Conversion Calculator

Calculate opioid doses with our online opioid conversion calculator. Convert opioid doses to MME with simple steps, clear results, and easy dose math.

Clinical Safety Notice: This calculator produces an estimated equianalgesic conversion based on published Morphine Milligram Equivalent (MME) conversion factors. It is not an automatically safe or exact starting dose. Opioid rotation requires clinical judgment due to incomplete cross-tolerance, individual patient variability, formulation and route differences, and special pharmacokinetics for methadone and fentanyl. This tool does not provide personalized medical advice.
MME/day = Current Dose/day × Conversion Factor
e.g. every 6 hours = 4 doses/day
MME Conversion Factor Reference (CDC Methodology)
OpioidConversion FactorNotes
Morphine (oral)1Reference opioid for MME
Hydrocodone (oral)1
Oxycodone (oral)1.5
Hydromorphone (oral)4
Oxymorphone (oral)3
Codeine (oral)0.15
Tramadol (oral)0.1
Tapentadol (oral)0.4
Methadone (oral)4 / 8 / 10 / 12Dose-dependent: ≤20mg/day=4, 21–40=8, 41–60=10, ≥61=12
Fentanyl (transdermal)2.4Applied to mcg/hour, not mg/day
⚠ Source: CDC Morphine Milligram Equivalent (MME) conversion methodology, as used in the CDC Guideline for Prescribing Opioids. These are standard published equianalgesic conversion factors — not a substitute for clinical judgment, specialist consultation, or individualized patient assessment. Methadone conversion to another opioid is intentionally not auto-calculated due to its non-linear, dose-dependent pharmacokinetics.
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An opioid conversion calculator can help check opioid dose math. It can show a dose as MME. MME means morphine milligram equivalent.

We made this calculator so users can check opioid math with ease. It can help with dose checks and dose review. But MME is a guide, not a new dose.

Opioid Conversion Formula

The main MME formula is:

MME per day = daily opioid dose × MME factor

The CDC lists these key factors. Hydrocodone is 1.0. Oxycodone is 1.5. Morphine is 1.0. Codeine is 0.15. Hydromorphone is 5.0. Methadone is 4.7. Tramadol is 0.2. Tapentadol is 0.4. Oxymorphone is 3.0. A fentanyl skin patch uses 2.4 per mcg/hour.

These factors are for pain care. They are not for opioid use disorder care.

A key point matters here. MME is not a direct swap dose. The CDC says these dose links are only estimates. A new opioid dose may need to be much lower. This is due to cross-tolerance and other drug and user factors. Methadone and fentanyl need extra care.

How to Use the Online Opioid Conversion Calculator

  1. Pick the opioid you use now. Choose it from the list.
  2. Enter the dose. Use the daily dose if the tool asks for it.
  3. Check the unit. Most drugs use mg/day. A fentanyl patch uses mcg/hour.
  4. Pick a new opioid if the tool has a switch check. Treat the result as an aid, not a new dose.
  5. Read the MME and notes. Check the drug label and care guide too.

Example Opioid Conversion Calculation

Say a user takes 20 mg of hydrocodone each day.

The CDC factor for hydrocodone is 1.0.

MME per day = 20 × 1.0

MME per day = 20 MME

So, 20 mg of hydrocodone each day is 20 MME with this factor. This does not mean 20 MME is the right dose of a new drug. A drug swap needs a full care check.

Final Verdict

An opioid conversion calculator can make dose math fast and clear. It can help you check MME with less work. It should not take the place of a care team. Always check the drug label and care guide before a drug swap.

FAQs

What is an opioid conversion calculator?

It is a tool that helps check opioid dose math. It can show a dose as MME.

What is the opioid conversion formula?

For MME, take the daily dose and multiply it by the MME factor.

Is MME the same as a new opioid dose?

No. MME is an estimate for dose checks. It is not a direct new dose.

Why is fentanyl not the same?

A skin patch uses mcg/hour. Most drugs in the CDC table use mg/day.

Why does methadone need care?

Methadone can stay in the body for a long time. Its risk can also last longer than its pain relief. So, a swap can be hard to judge.